HORDB

ID: hor001161
Uniprot ID: D9I8P2
Protein name: PeptTL
Gene name: AFP-13
Organism: Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Family: FARP (FMRFamide related peptide) family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Ascaris (genus), Ascarididae (family), Ascaridoidea (superfamily), Ascaridomorpha (infraorder), Spirurina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: TNIMGENRLNRNL
Length: 13
Propeptide: MAINSISCLITMLAITVAVSTLESSEIRMLESEFLDGKRGNSYRSFFNPNEYTVVERRDSKLMDPLIRFGKRTNIMGENRLNRNLRAEGLSSPLIRFGKRTPPEEDLLGRFTRDPQQRIVTDETVLRFGRSSAPAAA
Signal peptide: MAINSISCLITMLAITVAVSTLES
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001161_AF2.pdb

hor001161_ESM.pdb

Mass:	175897	Formula:	C62H109N23O21S
Absent amino acids:	ACDFHKPQSVWY	Common amino acids:	N
pI:	10.4	Basic residues:	2
Polar residues:	6	Hydrophobic residues:	3
Hydrophobicity:	-104.62	Boman Index:	-4773
Half-Life:	7.2 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	90
Instability Index:	3516.15	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 21524146
Title: Discovery of Neuropeptides in the Nematode Ascaris Suum by Database Mining and Tandem Mass Spectrometry